PRP Injections vs 2000 Graft Hair Transplant: A Medical Comparison of Results and Cost

Understanding the Differences in Mechanism and Outcome

Platelet-Rich Plasma (PRP) and Follicular Unit Extraction (FUE) hair transplantation represent two entirely distinct approaches to managing hair loss. While both are used commonly across the UK, their intended mechanisms, indications, long-term outcomes, and costs vary significantly. PRP injections involve extracting the patient's own blood, centrifuging it to concentrate the platelets, and injecting the resultant plasma into the scalp. These platelets release growth factors, which stimulate dormant follicles, promote healing, and enhance follicular thickness.

Hair transplantation, specifically using the FUE method, involves extracting individual follicular units from the donor region—typically the occipital scalp—and reimplanting them into balding or thinning areas. In the context of a 2000 graft procedure, this equates to roughly 4000 hairs. The objective is to redistribute genetically permanent hair to areas affected by androgenetic alopecia. It is not a regenerative treatment but rather a surgical redistribution.

Comparative Efficacy in Clinical Outcomes

One of the most critical differences lies in the reliability of results. PRP injections are non-surgical and may support follicular density, particularly in early-stage androgenetic alopecia, but evidence shows that the outcomes are variable and often temporary. A systematic review published in the journal Aesthetic Plastic Surgery in 2020 evaluated 12 randomised clinical trials and concluded that while PRP may lead to a modest increase in hair count and thickness, results were inconsistent across individuals. The full paper can be accessed here: https://pubmed.ncbi.nlm.nih.gov/32383137.

FUE hair transplantation offers a more predictable outcome, especially for patients with significant hair loss who are no longer responding to medical therapies. The implanted hairs are permanent, with survival rates commonly cited between 85% to 95%, depending on surgical technique and post-operative care. Longitudinal studies have confirmed the durability of results over many years. Unlike PRP, the results of a hair transplant are not dependent on the variable biology of follicle responsiveness to cytokines or growth factor signalling but on the successful transfer of active follicles.

Candidate Selection: Who Benefits More from Each?

PRP is best suited to younger patients in the early stages of hair thinning, particularly those who are not yet candidates for surgical intervention. It is sometimes used as an adjunct to finasteride and topical therapies. Patients with diffuse thinning or telogen effluvium may also benefit, although evidence in non-androgenetic forms of alopecia remains limited.

In contrast, a 2000 graft FUE hair transplant is most appropriate for patients with Norwood stage 3 to 5 pattern hair loss, where visible scalp exposure exists. PRP is unlikely to offer significant regrowth in these individuals. Many patients with well-defined areas of baldness and good donor density derive a permanent cosmetic improvement from surgery, whereas PRP would offer only temporary or minimal thickening.

Comparing Cost and Treatment Timelines

In the UK, PRP is marketed as a less expensive option, with one session costing between £300 to £500. However, multiple sessions are required—commonly 3 to 6 initially, followed by maintenance every 3 to 6 months. Over the course of a year, a patient may spend £1500 to £3000 or more, with no guarantee of sustained results.

By contrast, a 2000 graft FUE transplant typically costs £3699 at My Hair UK Clinics. This is a one-time intervention, with permanent results that can last a lifetime. While more expensive upfront, it is cost-effective long term when considering the durability of outcome and reduced need for ongoing treatments. The recovery period is approximately 7 to 10 days, with full growth evident by 12 months. PRP requires no downtime, but also no assurance of success.

PRP as Adjunct Rather Than Replacement

There is growing interest in combining PRP with FUE surgery to improve graft survival and post-operative healing. PRP is often applied intraoperatively or in the weeks following transplantation to enhance follicular anchorage and reduce post-surgical shedding. Studies such as the 2019 article in Dermatologic Surgery  suggest that adjunctive PRP may accelerate recovery and increase graft yield, though it remains optional rather than standard.

It is important to clarify to patients that PRP does not regenerate lost follicles in cases of total baldness. Once a follicle has miniaturised beyond viability or scarred, no amount of platelet stimulation will restore it. For this reason, surgical transplantation remains the gold standard in moderate to advanced androgenetic alopecia.

Patient Experience and Follow-Up Considerations

While PRP sessions are short and relatively painless, they require repeat visits, blood draws, and may involve localised swelling or bruising. Transplants involve surgical planning, anaesthesia, and a structured recovery protocol, including avoidance of strenuous activity, infection control, and adherence to graft care routines.

From a psychological perspective, the immediacy of visible improvement after a hair transplant (once full growth occurs) provides a level of satisfaction often unmatched by PRP. Patients report a greater sense of closure with surgery, compared to the ongoing uncertainty that sometimes accompanies regenerative therapies.

Final Thoughts from a Clinical Perspective

Both treatments have their place, but they are not interchangeable. PRP is not a replacement for transplantation. For men and women seeking a definitive correction to hair loss in targeted areas, especially those with well-established balding, a 2000 graft hair transplant offers long-term predictability, permanence, and cost-effectiveness.

Patients must be educated about the limitations of PRP and the surgical requirements of transplantation. The decision must rest on clinical staging, donor area assessment, and patient preference. Where possible, PRP may serve as a useful bridge or adjunct, but not a substitute for those requiring graft-based restoration.

FAQ

How much does a hair transplant cost in the UK?
The cost for a 2000 graft FUE hair transplant in the UK is around £3699 at My Hair UK. Other clinics may charge between £4500 and £7000 for the same procedure.

Is PRP cheaper than a hair transplant?
Yes, but only in the short term. A single PRP session costs £300 to £500, but repeated treatments are needed, making annual costs comparable to surgery without permanent results.

Can PRP replace a hair transplant?
No. PRP may enhance existing hair or support early-stage thinning, but it cannot restore hair in bald areas. Transplants are required for permanent results.

Do PRP results last?
PRP results typically last 4 to 6 months, requiring maintenance injections. Some patients do not respond at all.

Can I have PRP after a hair transplant?
Yes. PRP can support graft healing and early regrowth when used after FUE surgery. It is optional and not necessary for success.